Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402000 | 1.00 | TRPA1 (0.48) | TRPA1LMNAHSD17B10CA2CA1 | |
| SCHEMBL8383097 | 0.81 | CA12 (0.45) | LMNAHSD17B10CA2CA1CA12 | |
| SCHEMBL9835782 | 0.81 | CA12 (0.45) | LMNAHSD17B10CA2CA1CA12 | |
| SCHEMBL8646849 | 0.80 | LMNA (0.39) | TRPA1LMNAHSD17B10CA2CA1 | |
| SCHEMBL8644079 | 0.79 | LMNA (0.38) | TRPA1LMNAHSD17B10CA2CA1 | |
| SCHEMBL8645873 | 0.75 | NPSR1 (0.44) | LMNACA2CA1MAPTESR2 | |
| SCHEMBL8382753 | 0.74 | TRPA1 (0.44) | TRPA1LMNACA1CA12CA9 | |
| SCHEMBL19323907 | 0.73 | KMT2A (0.48) | TRPA1LMNAHPGDMEN1ALDH1A1 | |
| SCHEMBL19323897 | 0.73 | KMT2A (0.48) | TRPA1LMNAHPGDMEN1ALDH1A1 | |
| SCHEMBL4378592 | 0.72 | KDM4E (0.59) | LMNAHSD17B10CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |