Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806535 | 0.79 | POLB (0.41) | POLBMAPTHPGDCNR1LMNA | |
| SCHEMBL5154201 | 0.79 | POLB (0.41) | POLBMAPTHPGDCNR1LMNA | |
| SCHEMBL998208 | 0.79 | AKR1C2 (0.46) | POLBMAPTHPGDCNR1LMNA | |
| SCHEMBL8671570 | 0.78 | POLB (0.40) | POLBMAPTHPGDCNR1LMNA | |
| SCHEMBL5154300 | 0.78 | POLB (0.38) | POLBMAPTHPGDCNR1LMNA | |
| Potassium SCHEMBL11436513 | 0.77 | POLB (0.41) | POLBMAPTHPGDCNR1LMNA | |
| SCHEMBL9797202 | 0.77 | ALOX5 (0.45) | POLBMAPTLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5805761 | 0.77 | KRAS (0.43) | POLBMAPTHPGDCNR1LMNA | |
| Water SCHEMBL11448361 | 0.76 | POLB (0.41) | POLBMAPTHPGDCNR1LMNA | |
| Water SCHEMBL11448359 | 0.76 | POLB (0.41) | POLBMAPTHPGDCNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756531-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-26 | — | — | US | disclosed |