Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643282 | 0.79 | L3MBTL1 (0.43) | LMNACYP2D6MAPTALDH1A1ACHE | |
| SCHEMBL8788519 | 0.73 | ALDH1A1 (0.43) | LMNACYP2D6MAPTALDH1A1MAOB | |
| Fumaric Acid SCHEMBL8644566 | 0.72 | MEN1 (0.38) | LMNACYP1A2CYP2D6MAPTCYP3A4 | |
| Fumaric Acid SCHEMBL8644575 | 0.72 | MEN1 (0.38) | LMNACYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL8649409 | 0.70 | MC4R (0.41) | LMNACYP1A2CYP2D6MAPTMAOB | |
| SCHEMBL8649404 | 0.66 | SMN1; SMN2 (0.40) | LMNACYP2D6MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8787716 | 0.64 | L3MBTL1 (0.40) | LMNACYP2D6MAPTCYP3A4ALDH1A1 | |
| Fumaric Acid SCHEMBL11709158 | 0.62 | ALDH1A1 (0.47) | LMNACYP1A2CYP2D6MAPTCYP3A4 | |
| Fumaric Acid SCHEMBL11709154 | 0.62 | ALDH1A1 (0.47) | LMNACYP1A2CYP2D6MAPTCYP3A4 | |
| SCHEMBL8646569 | 0.61 | TDP1 (0.43) | LMNACYP1A2CYP2D6MAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0753514-A1 | ALKYLENEDIAMINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-01-15 | — | — | EP | disclosed |