Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | EDNRB | P24530 | 2/20 | 0.30 |
| ▸ | EDNRA | P25101 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1927671 | 0.86 | CA2 (0.41) | POLBPTGS2CA12CA1CA2 | |
| SCHEMBL1927038 | 0.77 | ALDH1A1 (0.31) | POLBCA12CA1CA2CA7 | |
| SCHEMBL1927669 | 0.77 | POLB (0.31) | POLBCA12CA1CA2CA7 | |
| SCHEMBL3059991 | 0.77 | POLB (0.34) | POLBIDO1TDO2CA12CA1 | |
| Hydrochloric Acid SCHEMBL28079593 | 0.76 | POLB (0.33) | POLBCA12CA1CA2CA7 | |
| Pivalate SCHEMBL15953987 | 0.75 | LMNA (0.40) | POLBPTGS2IDO1TDO2CA12 | |
| SCHEMBL19436422 | 0.74 | LMNA (0.37) | PTGS2CES1 | |
| SCHEMBL23569219 | 0.74 | CA2 (0.35) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL8229612 | 0.74 | CA1 (0.45) | POLBCA12CA1CA2CA7 | |
| SCHEMBL7335685 | 0.72 | POLB (0.32) | POLBCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109441-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |
| EP-0435794-A1 | Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides | RHONE-POULENC AGROCHIMIE (FR) | 1991-07-03 | — | — | EP | disclosed |
| US-4639265-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-27 | — | — | US | disclosed |
| EP-0064804-B1 | THIOPHENE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4547217-A | ESPECIALLY FOR CORN | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-15 | — | — | US | disclosed |
| US-4441910-A | PRE- AND POST-EMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-10 | — | — | US | disclosed |
| EP-0064804-A2 | Thiophene herbicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-17 | — | — | EP | disclosed |