Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24278914 | 1.00 | LMNA (0.41) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8645438 | 0.81 | MAPT (0.50) | LMNAMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22925150 | 0.81 | RAB9A (0.54) | LMNAMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL1614008 | 0.79 | GRIN2D (0.40) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17560756 | 0.78 | LMNA (0.47) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17560757 | 0.78 | LMNA (0.47) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19434705 | 0.77 | LMNA (0.46) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17598764 | 0.77 | LMNA (0.46) | LMNAANO1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31136730 | 0.76 | PDE2A (0.39) | LMNAMAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17560971 | 0.76 | LMNA (0.45) | LMNAANO1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862558-A1 | SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997015559-A1 | SUBSTITUTED 4,5-DI(TRIFLUOROMETHYL)PYRAZOLES AND THEIR USE AS HERBICIDES AND FOR DESICCATING/DEFOLIATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |