Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842730 | 0.72 | MMP2 (0.40) | FDPSALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8842518 | 0.72 | MMP2 (0.40) | FDPSALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8648798 | 0.71 | FDPS (0.55) | FDPSMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL8644746 | 0.70 | CPN1 (0.38) | — | |
| SCHEMBL27602300 | 0.69 | FDPS (0.41) | FDPSSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8842533 | 0.69 | FDPS (0.32) | FDPSGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7284064 | 0.69 | MEN1 (0.41) | MEN1KMT2AALDH1A1SLC6A3SLC6A2 | |
| SCHEMBL10775306 | 0.69 | MEN1 (0.41) | MEN1KMT2AALDH1A1SLC6A3SLC6A2 | |
| SCHEMBL7284071 | 0.69 | MEN1 (0.41) | MEN1KMT2AALDH1A1SLC6A3SLC6A2 | |
| SCHEMBL7380569 | 0.69 | MEN1 (0.41) | MEN1KMT2AALDH1A1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703919-B1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-02 | — | — | EP | claimed |
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |