Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929955 | 1.00 | HDAC8 (0.42) | HDAC8PTPN1CYP2C9CA12CA1 | |
| SCHEMBL28574091 | 0.90 | HDAC8 (0.50) | HDAC8PTPN1CYP2C9CA12CA1 | |
| SCHEMBL12124388 | 0.80 | APP (0.55) | CYP2C9CA12CA1CA2CA9 | |
| SCHEMBL15975757 | 0.79 | ESR1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL15975758 | 0.79 | ESR1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL126319 | 0.79 | ESR1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12879524 | 0.79 | ESR1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL103830 | 0.79 | ESR1 (0.43) | CA12CA1CA2CA4CA9 | |
| SCHEMBL480205 | 0.78 | APP (0.60) | CYP2C9CA12CA1CA2CA9 | |
| SCHEMBL12124384 | 0.78 | APP (0.60) | CYP2C9CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10300697-A | — | — | None | — | — | JP | disclosed |
| US-9346768-B2 | Molecular glasses with functionalizable groups | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE (CA) | 2016-05-24 | — | — | US | disclosed |
| US-9346768-B2 | Molecular glasses with functionalizable groups | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE (CA) | 2016-05-24 | — | — | US | disclosed |
| US-9328076-B2 | Molecular glasses with functionalizable groups | HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) | 2016-05-03 | — | — | US | disclosed |
| US-9328076-B2 | Molecular glasses with functionalizable groups | HER MAJESTY IN THE RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF DEFENSE (CA) | 2016-05-03 | — | — | US | disclosed |
| US-20150232433-A1 | Molecular Glasses With Functionalizable Groups | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) | 2015-08-20 | — | — | US | disclosed |
| US-20150232433-A1 | Molecular Glasses With Functionalizable Groups | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) | 2015-08-20 | — | — | US | disclosed |
| US-20140005370-A1 | MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS | HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENCE (CA) | 2014-01-02 | — | — | US | disclosed |
| JP-H10300697-A | GAS SENSOR | SHIMADZU CORP | 1998-11-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005370-A1 | MOLECULAR GLASSES WITH FUNCTIONALIZABLE GROUPS | GNG2, GDI1, F12 | HDAC8 4268/4885PTPN1 1125/4885CYP2C9 4718/4885 |
| US-20150232433-A1 | Molecular Glasses With Functionalizable Groups | GDI1, GNG2, F12 | HDAC8 4299/4885PTPN1 1317/4885CYP2C9 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.