SCHEMBL8647447

SCHEMBL8647447

CC[Si](CC)(CC)Oc1cccc([S+](c2ccccc2)c2cccc(O[Si](CC)(CC)CC)c2)c1.O=S(=O)([O-])c1ccc(F)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
FFAR1 O14842 2/20 0.35
NR3C1 P04150 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
F2 P00734 1/20 0.34
CETP P11597 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
IKBKB O14920 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
AR P10275 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8648338 0.89 KMT2A (0.40) TSHRMAPK1KMT2AHSD17B10FFAR1
SCHEMBL8325629 0.83 LTA4H (0.31) L3MBTL1
SCHEMBL8649984 0.83
SCHEMBL8644644 0.80 FFAR1 (0.37) FFAR1NR3C1FFAR4L3MBTL1NPSR1
SCHEMBL8323442 0.77 ESR1 (0.31)
SCHEMBL2955279 0.76 PKM (0.46) TSHRMAPK1KMT2AHSD17B10FFAR1
SCHEMBL8651780 0.75 F2 (0.41) MAPK1KMT2AL3MBTL1F2SMN1; SMN2
SCHEMBL8651559 0.75 PKM (0.35) TSHRMAPK1FFAR1FFAR4F2
SCHEMBL8651776 0.74 CA2 (0.34) TSHRMAPK1KMT2AF2CETP
SCHEMBL8647451 0.74 KMT2A (0.38) TSHRMAPK1KMT2AHSD17B10FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5824824-A AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-10-20 US disclosed