SCHEMBL8647553

SCHEMBL8647553

C[Si](C)(NC(N)=O)NC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.39
TSHR P16473 2/20 0.39
NFKB1 P19838 2/20 0.39
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
THPO P40225 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
CRBN Q96SW2 1/20 0.38
ALOX15 P16050 1/20 0.35
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607730 0.80
Hydrogen Peroxide SCHEMBL29498107 0.78 LMNA (0.37) LMNATSHRNFKB1BLMPMP22
SCHEMBL7757333 0.71 CRBN (0.32) LMNATSHRNFKB1BLMPMP22
SCHEMBL8589039 0.71 CRBN (0.32) LMNATSHRNFKB1BLMPMP22
SCHEMBL8650618 0.69 TSHR (0.35) LMNATSHRNFKB1BLMPMP22
SCHEMBL9156676 0.69 CRBN (0.31) LMNATSHRNFKB1BLMPMP22
SCHEMBL451023 0.69 KDM4E (0.41) LMNATSHRNFKB1THPOCA2
SCHEMBL27934699 0.69 CRBN (0.56) LMNATSHRNFKB1BLMPMP22
SCHEMBL5789591 0.67 TSHR (0.35) LMNATSHRNFKB1BLMPMP22
SCHEMBL8652162 0.67 LMNA (0.33) LMNATSHRNFKB1BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509548-B2 Alkoxylated polymers SUN CHEMICAL CORPORATION (US) 2025-12-30 US claimed
US-20240239957-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2024-07-18 US claimed
US-11912821-B2 Alkoxylated polymers SUN CHEMICAL CORPORATION (US) 2024-02-27 US claimed
US-11078336-B2 Alkoxylated dispersing agents SUN CHEMICAL CORPORATION (US) 2021-08-03 US claimed
EP-3373926-B1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORP (US) 2020-06-10 EP claimed
US-20190322813-A1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORPORATION (US) 2019-10-24 US claimed
EP-3145963-B1 ALKOXYLATED POLYMERS SUN CHEMICAL CORP (US) 2019-07-10 EP claimed
US-20190144604-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2019-05-16 US claimed
EP-3373926-A1 ALKOXYLATED DISPERSING AGENTS Sun Chemical Corporation (US) 2018-09-19 EP claimed
WO-2017083321-A1 ALKOXYLATED DISPERSING AGENTS SUN CHEMICAL CORPORATION (US) 2017-05-18 WO claimed
US-20170101505-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2017-04-13 US claimed
EP-3145963-A1 ALKOXYLATED POLYMERS Sun Chemical Corporation (US) 2017-03-29 EP claimed
WO-2015179626-A1 ALKOXYLATED POLYMERS SUN CHEMICAL CORPORATION (US) 2015-11-26 WO claimed
EP-0547321-B1 Method for preparation of very high molecular weight polycarborane siloxanes HUGHES AIRCRAFT CO (US) 1996-01-24 EP claimed
EP-0576812-B1 A low temperature vulcanizing carborane siloxane adhesive HUGHES AIRCRAFT CO (US) 1995-11-08 EP claimed
EP-0576812-A2 A low temperature vulcanizing carborane siloxane adhesive Hughes Aircraft Company (US) 1994-01-05 EP claimed
EP-0547321-A1 Method for preparation of very high molecular weight polycarborane siloxanes Hughes Aircraft Company (US) 1993-06-23 EP claimed
US-5208310-A Method for preparation of very high molecular weight polycarborane siloxanes HUGHES AIRCRAFT COMPANY (US) 1993-05-04 US claimed
JP-5262878-A None JP disclosed
EP-0402632-A2 Aromatic polyimide silanol compounds, precursors and polymers thereof Hughes Aircraft Company (US) 1990-12-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509548-B2 Alkoxylated polymers PLOD3, UROD, HAO2 LMNA 705/4885TSHR 3993/4885NFKB1 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.