Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.67 |
| ▸ | HTR7 | P34969 | 12/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111481 | 0.85 | HTR7 (0.66) | SLC6A9HTR7CCR1HTR6TSHR | |
| SCHEMBL8643575 | 0.82 | HTR7 (0.70) | SLC6A9HTR7HRH3 | |
| SCHEMBL11101165 | 0.81 | HTR7 (0.67) | HTR7CCR1HTR6TSHR | |
| SCHEMBL8552320 | 0.81 | HTR7 (0.70) | SLC6A9HTR7CCR1HTR6TSHR | |
| SCHEMBL14382102 | 0.81 | SLC6A9 (1.00) | SLC6A9HTR7 | |
| SCHEMBL14382140 | 0.81 | SLC6A9 (1.00) | SLC6A9HTR7 | |
| Hydrochloric Acid SCHEMBL11104579 | 0.80 | SLC6A9 (0.54) | SLC6A9HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL11111993 | 0.80 | HTR7 (0.67) | HTR7CCR1HTR6TSHR | |
| SCHEMBL11108893 | 0.80 | SLC6A9 (0.67) | SLC6A9HTR7CCR1 | |
| SCHEMBL25759707 | 0.79 | BCHE (0.63) | HTR7CCR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883613-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-12-16 | — | — | EP | claimed |
| WO-1997029097-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-14 | — | — | WO | claimed |