Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647376 | 0.90 | TSHR (0.41) | TSHRHTTLMNAKMT2AMEN1 | |
| SCHEMBL7370518 | 0.79 | F2 (0.53) | TSHRHTTLMNAKMT2AMEN1 | |
| SCHEMBL8644824 | 0.71 | MEN1 (0.48) | TSHRLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL10918866 | 0.69 | KMT2A (0.76) | HTTLMNAKMT2AMEN1GLA | |
| SCHEMBL6747815 | 0.61 | CYP1A2 (0.43) | HTTLMNAKMT2AMEN1GAA | |
| SCHEMBL2569357 | 0.60 | ALDH1A1 (0.65) | HTTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL6086898 | 0.59 | HTT (0.48) | TSHRHTTLMNAKMT2AMEN1 | |
| SCHEMBL6488101 | 0.58 | KDM4E (0.42) | LMNAKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL25852986 | 0.57 | RAB9A (0.63) | TSHRLMNAATMKDM4ESMN1; SMN2 | |
| SCHEMBL25517569 | 0.56 | L3MBTL1 (0.65) | HTTLMNAKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |