Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655154 | 0.93 | HCRTR2 (0.33) | HCRTR1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL8652559 | 0.88 | KCNQ3 (0.34) | HCRTR1 | |
| SCHEMBL8652681 | 0.86 | CNR1 (0.32) | — | |
| SCHEMBL8652603 | 0.85 | USP30 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL8655139 | 0.85 | F10 (0.32) | — | |
| SCHEMBL8676079 | 0.83 | CCKBR (0.35) | BDKRB1 | |
| SCHEMBL8482395 | 0.83 | MAPT (0.38) | HCRTR1 | |
| SCHEMBL8650737 | 0.82 | POLB (0.32) | — | |
| SCHEMBL8648884 | 0.82 | — | — | |
| SCHEMBL8652573 | 0.82 | DRD2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |