Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655154 | 0.87 | HCRTR2 (0.33) | — | |
| SCHEMBL8482395 | 0.87 | MAPT (0.38) | KDM4EALDH1A1LMNA | |
| SCHEMBL8652603 | 0.85 | USP30 (0.34) | — | |
| SCHEMBL8655139 | 0.85 | F10 (0.32) | — | |
| SCHEMBL8648889 | 0.85 | CHRNA7 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8676079 | 0.85 | CCKBR (0.35) | ALDH1A1 | |
| SCHEMBL8652573 | 0.85 | DRD2 (0.30) | — | |
| SCHEMBL8648884 | 0.83 | — | — | |
| SCHEMBL8649546 | 0.82 | HCRTR1 (0.34) | — | |
| SCHEMBL8666557 | 0.82 | CCKBR (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |