Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666557 | 0.98 | CCKBR (0.34) | CCKBRCCR3EPHX2ALDH1A1UBE2M | |
| SCHEMBL8655308 | 0.86 | KCNQ3 (0.32) | — | |
| SCHEMBL8648884 | 0.85 | — | — | |
| SCHEMBL8482395 | 0.85 | MAPT (0.38) | CCR3ALDH1A1 | |
| SCHEMBL8655154 | 0.85 | HCRTR2 (0.33) | — | |
| SCHEMBL8479118 | 0.85 | OPRK1 (0.32) | — | |
| SCHEMBL8650737 | 0.85 | POLB (0.32) | ALDH1A1 | |
| SCHEMBL8655139 | 0.84 | F10 (0.32) | — | |
| SCHEMBL8652603 | 0.83 | USP30 (0.34) | — | |
| SCHEMBL8649546 | 0.83 | HCRTR1 (0.34) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1729-H | Method for preparing compounds employing solid phase synthesis and novel linker-resin | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |