Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647661 | 0.87 | ENPP3 (0.40) | ENPP3ENPP1ENPP2TSHRKDM4E | |
| SCHEMBL8645327 | 0.84 | KAT6A (0.34) | TP53DHFRHSD11B1TSHRDDB1 | |
| SCHEMBL8645085 | 0.81 | DHFR (0.37) | DHFRHSD11B1TSHRDDB1CRBN | |
| SCHEMBL8649688 | 0.80 | TSHR (0.38) | TP53DHFRHSD11B1TSHRDDB1 | |
| SCHEMBL8319790 | 0.80 | DDB1 (0.39) | TP53DHFRHSD11B1TSHRDDB1 | |
| SCHEMBL8649231 | 0.78 | TP53 (0.41) | TP53DHFRHSD11B1TSHRKDM4E | |
| SCHEMBL8648971 | 0.78 | TSHR (0.36) | TP53DHFRHSD11B1TSHRDDB1 | |
| SCHEMBL8649659 | 0.77 | DHFR (0.40) | DHFRHSD11B1TSHRDDB1CRBN | |
| SCHEMBL8321361 | 0.77 | GAA (0.37) | TP53DHFRHSD11B1TSHRDDB1 | |
| SCHEMBL8319160 | 0.76 | HSD11B1 (0.41) | DHFRHSD11B1DDB1CRBNMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |