Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654368 | 0.91 | DRD2 (0.38) | SLC6A12DRD4CNR1CNR2 | |
| SCHEMBL8648481 | 0.88 | CCR3 (0.39) | MCHR1CNR1CNR2 | |
| SCHEMBL8485545 | 0.87 | NPSR1 (0.40) | SLC6A12POLBMCHR1 | |
| SCHEMBL8484461 | 0.85 | NPSR1 (0.39) | SLC6A12POLBMCHR1 | |
| SCHEMBL8717987 | 0.85 | CCR3 (0.44) | SLC6A12DRD4CNR1CNR2 | |
| SCHEMBL8712541 | 0.83 | CCR3 (0.44) | SLC6A12DRD4 | |
| SCHEMBL8665883 | 0.83 | NPSR1 (0.37) | POLBDRD4MCHR1 | |
| SCHEMBL8713186 | 0.82 | DRD2 (0.36) | MCHR1 | |
| SCHEMBL8651963 | 0.81 | CNR1 (0.40) | SLC6A12POLBDRD4CNR1CNR2 | |
| SCHEMBL8665520 | 0.81 | CCR3 (0.42) | SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |