Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651970 | 0.88 | SLC6A12 (0.36) | CNR1CNR2MCHR1 | |
| SCHEMBL8485545 | 0.88 | NPSR1 (0.40) | CCR3SIGMAR1MCHR1 | |
| SCHEMBL8717987 | 0.87 | CCR3 (0.44) | CCR3CNR1CNR2HTR1ADRD2 | |
| SCHEMBL8654368 | 0.86 | DRD2 (0.38) | CCR3CNR1CNR2DRD2CYP3A4 | |
| SCHEMBL8484461 | 0.85 | NPSR1 (0.39) | CCR3SIGMAR1MCHR1 | |
| SCHEMBL8712541 | 0.85 | CCR3 (0.44) | CCR3HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8665883 | 0.83 | NPSR1 (0.37) | CCR3DRD2MCHR1 | |
| SCHEMBL8483744 | 0.83 | CCR3 (0.44) | CCR3ALDH1A1HTR7SIGMAR1MCHR1 | |
| SCHEMBL8665520 | 0.83 | CCR3 (0.42) | CCR3HTR1ADRD2HTR7HTR6 | |
| SCHEMBL8713186 | 0.83 | DRD2 (0.36) | ALDH1A1DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |