Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.42 |
| ▸ | AR | P10275 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768109 | 0.86 | PGR (0.47) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8767958 | 0.79 | NR3C1 (0.42) | PGRNR3C1ARCYP3A4CYP17A1 | |
| SCHEMBL8541047 | 0.79 | PGR (0.48) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8540722 | 0.79 | ALDH1A1 (0.49) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8538113 | 0.78 | PGR (0.47) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8536387 | 0.77 | PGR (0.51) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8536181 | 0.77 | PGR (0.49) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8653889 | 0.77 | PGR (0.44) | PGRNR3C1ARCYP3A4CYP17A1 | |
| SCHEMBL9019827 | 0.77 | NR3C1 (0.59) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL5498124 | 0.77 | PGR (0.49) | PGRNR3C1ARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | claimed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | claimed |
| EP-0567472-B1 | D-HOMO-(16-EN)-11 BETA-ARYL-4-ESTRENES, PROCESS FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | SCHERING AG (DE) | 1998-10-07 | — | — | EP | disclosed |
| US-5519027-A | PROGESTERONE ANTAGONIST FOR OXYTOCICS OR PREVENTION OF TERMINATION OF PREGNANCY | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |