Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483686 | 0.89 | CNR1 (0.37) | CCR3MEN1KMT2APOLBNPSR1 | |
| SCHEMBL8717984 | 0.89 | CCR3 (0.42) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8712539 | 0.86 | CCR3 (0.42) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8665519 | 0.85 | CCR3 (0.40) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8665528 | 0.83 | CCR3 (0.40) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8653114 | 0.80 | CCR3 (0.42) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8653118 | 0.77 | CCR3 (0.43) | CCR3HTR7HPGDSHTR1ADRD2 | |
| SCHEMBL8662771 | 0.77 | TSHR (0.33) | CCR3ALDH1A1TSHR | |
| SCHEMBL8481557 | 0.77 | TSHR (0.31) | ALDH1A1TSHR | |
| SCHEMBL8482397 | 0.77 | CCR3 (0.35) | CCR3KDM5APOLBNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712279-A | Inhibitors of microsomal triglyceride transfer protein and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-01-27 | — | — | US | disclosed |