Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 7/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665519 | 0.98 | CCR3 (0.40) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8712539 | 0.96 | CCR3 (0.42) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8717984 | 0.94 | CCR3 (0.42) | CCR3KDM5AHTR7HTR1ADRD2 | |
| SCHEMBL8666097 | 0.89 | DRD2 (0.36) | DRD2 | |
| SCHEMBL8665881 | 0.87 | DRD2 (0.37) | DRD2 | |
| SCHEMBL8664872 | 0.86 | SMPD2 (0.37) | KDM5A | |
| SCHEMBL8482397 | 0.85 | CCR3 (0.35) | CCR3KDM5ATSHR | |
| SCHEMBL8668022 | 0.85 | FPR1 (0.36) | CCR3TSHR | |
| SCHEMBL8501050 | 0.83 | MTTP (0.36) | DRD2 | |
| SCHEMBL8653115 | 0.83 | CCR3 (0.43) | CCR3KDM5AHTR7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |