Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712539 | 0.98 | CCR3 (0.42) | CCR3HPGDSHTR7HTR1ADRD2 | |
| SCHEMBL8665519 | 0.96 | CCR3 (0.40) | CCR3HPGDSHTR7HTR1ADRD2 | |
| SCHEMBL8665528 | 0.94 | CCR3 (0.40) | CCR3HPGDSHTR7HTR1ADRD2 | |
| SCHEMBL8653115 | 0.89 | CCR3 (0.43) | CCR3HPGDSHTR7HTR1ADRD2 | |
| SCHEMBL8713182 | 0.88 | CKS1B (0.38) | HTR1ADRD2DRD3POLB | |
| SCHEMBL8482397 | 0.88 | CCR3 (0.35) | CCR3KDM5AKDM4EMTTPOPRM1 | |
| SCHEMBL8668022 | 0.88 | FPR1 (0.36) | CCR3NPSR1L3MBTL1TSHR | |
| SCHEMBL8648478 | 0.87 | CCNE1 (0.37) | CCR3MEN1KMT2AMTTPCHRM2 | |
| SCHEMBL8654366 | 0.86 | KMT2A (0.40) | DRD2MEN1KMT2AADRA2ASLC6A2 | |
| SCHEMBL8651966 | 0.85 | SLC6A12 (0.36) | DRD2MTTPCHRM2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |