Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8594205 | 0.91 | HSPB1 (0.44) | HSPB1SOS1MAOBMAPTS1PR2 | |
| SCHEMBL23391383 | 0.86 | LTA4H (0.48) | MAOBVEGFALTA4HFFAR4MEN1 | |
| SCHEMBL9458056 | 0.82 | RAB9A (0.49) | VEGFAMAPTGAAKDM4E | |
| SCHEMBL23657399 | 0.82 | VEGFA (0.37) | VEGFAMAPTS1PR2FFAR4EPAS1 | |
| SCHEMBL17606477 | 0.80 | MAOB (0.47) | MAOBVEGFAMAPTKDM4E | |
| SCHEMBL30564888 | 0.80 | MAOB (0.47) | MAOBVEGFAMAPTKDM4E | |
| SCHEMBL805908 | 0.80 | MAPT (0.58) | HSPB1SOS1MAOBMAPTSCN4A | |
| SCHEMBL9385639 | 0.80 | CYP2A6 (0.48) | MAOBMAPTGAAKDM4E | |
| SCHEMBL23649526 | 0.79 | SOS1 (0.44) | SOS1VEGFAFFAR4EPAS1 | |
| SCHEMBL29824710 | 0.79 | SOS1 (0.44) | SOS1VEGFAFFAR4EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710157-A | INSECTICIDES FOR AGRICULTURE | FMC CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5593998-A | 2,4-diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides | FMC CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| US-5547954-A | MIXED WITH AGRICULTURAL ACCEPTABLE CARRIER | FMC CORPORATION (US) | 1996-08-20 | — | — | US | disclosed |
| US-5532370-A | FOR INSECTS INCLUDING LARVAE SUCH AS TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |