Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26709197 | 0.86 | VEGFA (0.35) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL27018957 | 0.84 | RAB9A (0.53) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL8653265 | 0.82 | HSPB1 (0.41) | MAPTKDM4EVEGFAGAA | |
| SCHEMBL11608881 | 0.78 | MAPT (0.63) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL4787821 | 0.78 | RAB9A (0.63) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL17998024 | 0.78 | RAB9A (0.68) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL23391383 | 0.77 | LTA4H (0.48) | RAB9ANPC1VEGFA | |
| SCHEMBL26262687 | 0.76 | MAPT (0.52) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL427816 | 0.75 | RAB9A (0.77) | RAB9AALDH1A1NPC1HPGDMAPT | |
| SCHEMBL127279 | 0.75 | RAB9A (0.77) | RAB9AALDH1A1NPC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |