Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589483 | 0.82 | KMT2A (0.41) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL8646495 | 0.78 | KMT2A (0.39) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL7761358 | 0.78 | ALDH1A1 (0.39) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL8593176 | 0.74 | KMT2A (0.36) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL9095282 | 0.74 | MAPT (0.41) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL11405512 | 0.72 | KMT2A (0.41) | KMT2AMEN1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7761636 | 0.67 | TSHR (0.42) | KMT2AMEN1MAPTCYP3A4TSHR | |
| Biphenyl SCHEMBL28340467 | 0.67 | LMNA (0.42) | MAPTCYP3A4TSHRTDP1L3MBTL1 | |
| SCHEMBL5364559 | 0.65 | MAPT (0.42) | KMT2AMEN1MAPTCYP3A4TSHR | |
| SCHEMBL29840068 | 0.64 | GAA (0.67) | KMT2AMEN1MAPTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636163-B1 | CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS | MINNESOTA MINING & MFG (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5578380-A | Crosslinkable silarylene-siloxane copolymers | MINNESOTA MINING & MFG (US) | 1996-11-26 | — | — | US | disclosed |
| US-5346980-A | Crosslinkable silarylene-siloxane copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-13 | — | — | US | disclosed |