Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646495 | 0.75 | KMT2A (0.39) | KMT2ALMNAMEN1ALDH1A1BCAT2 | |
| SCHEMBL7761358 | 0.75 | ALDH1A1 (0.39) | KMT2ALMNAMEN1ALDH1A1BCAT2 | |
| SCHEMBL8653284 | 0.74 | KMT2A (0.41) | KMT2ALMNAMEN1ALDH1A1BCAT2 | |
| SCHEMBL8589483 | 0.74 | KMT2A (0.41) | KMT2ALMNAMEN1ALDH1A1BCAT2 | |
| SCHEMBL8763285 | 0.71 | ADH1B (0.38) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL9095282 | 0.70 | MAPT (0.41) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| SCHEMBL8589436 | 0.68 | LMNA (0.33) | LMNACYP3A4TSHRBLMPMP22 | |
| SCHEMBL14898478 | 0.67 | ESR1 (0.33) | MAPT | |
| SCHEMBL8763441 | 0.67 | TP53 (0.31) | ALDH1A1MAPTTDP1L3MBTL1POLB | |
| SCHEMBL31420254 | 0.64 | MAPT (0.43) | LMNAALDH1A1MAPTCYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830362-A4 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | disclosed |
| EP-0830362-A1 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040693-A1 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |