SCHEMBL865474

SCHEMBL865474

C=C(C)C(=O)OC([O])CCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 5/20 0.41
THRB P10828 1/20 0.38
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7242749 0.86 TSHR (0.50) ALDH1A1TSHRTHRBFAAH
SCHEMBL865654 0.85 TSHR (0.53) TSHRTHRBFAAH
SCHEMBL7237863 0.85 TSHR (0.53) TSHRTHRBFAAH
SCHEMBL11380508 0.83 TSHR (0.39) ALDH1A1TSHRTHRBFAAH
SCHEMBL867012 0.83 TSHR (0.43) ALDH1A1TSHRTHRBTDP1
SCHEMBL3413684 0.82 ALDH1A1 (0.43) ALDH1A1TSHRTHRBCHRM1AKR1A1
SCHEMBL11863394 0.81 ALDH1A1 (0.46) ALDH1A1TSHRTHRBHDAC7HDAC8
SCHEMBL142824 0.81 ALDH1A1 (0.46) ALDH1A1TSHRTHRBHDAC7HDAC8
SCHEMBL437295 0.79 TSHR (0.45) ALDH1A1TSHRTHRBCHRM1AKR1A1
SCHEMBL14871 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTHRBHDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143347-A1 OPTICAL ANISOTROPIC LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND AR DISPLAY DEVICE 富士フイルム株式会社 2024-07-04 WO disclosed
WO-2024143339-A1 OPTICAL ANISOTROPIC LAYER, LIGHT GUIDE ELEMENT, AND AR DISPLAY DEVICE 富士フイルム株式会社 2024-07-04 WO disclosed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
US-11977290-B2 Liquid crystal diffraction element, optical element, image display unit, head-mounted display, beam steering, and sensor FUJIFILM CORPORATION (JP) 2024-05-07 US disclosed
US-20240045334-A1 EXPOSURE METHOD OF PHOTOALIGNMENT LAYER FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-20240045335-A1 EXPOSURE METHOD OF PHOTOALIGNMENT LAYER FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
US-20240036343-A1 LIQUID CRYSTAL DIFFRACTION ELEMENT, IMAGE DISPLAY APPARATUS, AND HEAD MOUNTED DISPLAY FUJIFILM CORPORATION (JP) 2024-02-01 US disclosed
US-20230244012-A1 TRANSMISSIVE LIQUID CRYSTAL DIFFRACTION ELEMENT FUJIFILM CORPORATION (JP) 2023-08-03 US disclosed
US-20230229002-A1 OPTICAL ELEMENT, LIGHT GUIDE ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230229038-A1 LIQUID CRYSTAL DIFFRACTION ELEMENT, OPTICAL ELEMENT, IMAGE DISPLAY UNIT, HEAD-MOUNTED DISPLAY, BEAM STEERING, AND SENSOR FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed
EP-1966119-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2008-09-10 EP disclosed
EP-1860094-A1 Photocrosslinkable materials Rolic AG (CH) 2007-11-28 EP disclosed
WO-2007071091-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2007-06-28 WO disclosed
US-6589445-B2 Irradiating; changing twisting structure FUJI PHOTO FILM CO., LTD. (JP) 2003-07-08 US disclosed
US-20020033479-A1 Light-reaction type optically active compound, light-reaction type chiral agent, liquid crystal composition, liquid crystal color filter, optical film, recording medium, and method of changing twist structure of liquid crystal FUJI PHOTO FILM CO., LTD. 2002-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD ALDH1A1 313/4885TSHR 3933/4885THRB 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.