SCHEMBL867012

SCHEMBL867012

C=C(C)C(=O)OC([O])CC

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440616 0.84 TSHR (0.45) TSHRALDH1A1THRBTDP1
SCHEMBL865474 0.83 ALDH1A1 (0.44) TSHRALDH1A1THRBTDP1
Ammonia Solution, Strong SCHEMBL27784925 0.82 TSHR (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL618450 0.80 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL3413032 0.80 TSHR (0.42) TSHRALDH1A1THRB
Methylamine SCHEMBL27627991 0.80 TSHR (0.42) TSHRALDH1A1THRBTDP1
SCHEMBL601418 0.79 TSHR (0.45) TSHRALDH1A1THRBTDP1
SCHEMBL7242749 0.78 TSHR (0.50) TSHRALDH1A1THRB
SCHEMBL5068871 0.77 TSHR (0.43) TSHRALDH1A1THRBTDP1
SCHEMBL4362365 0.77 TSHR (0.43) TSHRALDH1A1THRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110740855-A Method for producing silicone hydrogel contact lenses 爱尔康公司 2020-01-31 CN claimed
EP-0162550-B1 HALOGEN-CONTAINING LENS MATERIAL KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-12-13 EP claimed
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 US disclosed
US-6984261-B2 Use of ceramics in dental and orthodontic applications 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-01-10 US disclosed
EP-1264865-B1 Addition-curable silicone composition with improved adhesion and cured silicone product DOW CORNING (US) 2004-05-12 EP disclosed
US-6512037-B1 Hydrosilylation addition-curable silicone composition containing a titanium or zirconium compound having at least one aliphatic carbon-carbon multiple bond DOW CORNING CORPORATION 2003-01-28 US disclosed
US-20030013802-A1 SILICONE COMPOSITION AND CURED SILICONE PRODUCT DOW CORNING CORPORATION 2003-01-16 US disclosed
EP-1264865-A1 Addition-curable silicone composition with improved adhesion and cured silicone product Dow Corning Corporation (US) 2002-12-11 EP disclosed
EP-0442796-A1 Optical component for applications in integrated optics THOMSON-CSF (FR) 1991-08-21 EP disclosed
EP-0415817-A1 Amorphous copolymers for use in non-linear optics THOMSON-CSF (FR) 1991-03-06 EP disclosed
US-4855282-A Recording material and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 1989-08-08 US disclosed
EP-0126029-B1 IMAGE-FORMING PROCESS CIBA-GEIGY AG (CH) 1987-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 TSHR 4828/4885ALDH1A1 97/4885THRB 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.