Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596285 | 0.86 | ALDH1A1 (0.37) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL3625418 | 0.82 | CD44 (0.39) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL30469485 | 0.82 | CD44 (0.39) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL2800809 | 0.81 | SMN1; SMN2 (0.43) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL476347 | 0.81 | CD44 (0.42) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL29380196 | 0.81 | SMN1; SMN2 (0.43) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL29589903 | 0.81 | CD44 (0.42) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL9617287 | 0.80 | CD44 (0.38) | CD44CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL2585650 | 0.78 | G6PD (0.39) | CYP3A4TSHRALDH1A1HPGDHSD17B10 | |
| SCHEMBL12724449 | 0.78 | MEN1 (0.53) | CD44CYP3A4TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834575-A | POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0628590-B1 | Polyimide having organopolysiloxane side chain | DOW CORNING (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5473041-A | Increased solubility and low melting points; separation films; diaminobiphenyl-modified polysiloxanes | DOW CORNING CORPORATION (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0628590-A2 | Polyimide having organopolysiloxane side chain | DOW CORNING CORPORATION (US) | 1994-12-14 | — | — | EP | disclosed |