Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659398 | 0.94 | HTR7 (0.37) | HTR7HSD17B10KDM4ESMN1; SMN2CHRM2 | |
| SCHEMBL8655982 | 0.91 | SIGMAR1 (0.38) | HTR7HSD17B10KDM4EALDH1A1NPSR1 | |
| SCHEMBL8661418 | 0.90 | SMN1; SMN2 (0.37) | HTR7HSD17B10KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8655407 | 0.89 | HTR7 (0.40) | HTR7HSD17B10KDM4EALDH1A1BCHE | |
| SCHEMBL8654724 | 0.89 | GAA (0.35) | HTR7HSD17B10KDM4ESMN1; SMN2CHRM2 | |
| SCHEMBL8654666 | 0.86 | HTR7 (0.39) | HTR7GRIN2BCHRM2CHRM1SIGMAR1 | |
| SCHEMBL8659057 | 0.86 | SMN1; SMN2 (0.37) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8656704 | 0.85 | GAA (0.33) | HTR7SMN1; SMN2CHRM2CHRM1SIGMAR1 | |
| SCHEMBL8659308 | 0.85 | SIGMAR1 (0.35) | HTR7ALDH1A1CHRM2CHRM1SIGMAR1 | |
| SCHEMBL8659391 | 0.84 | HTR7 (0.39) | HTR7HSD17B10KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |