Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655832 | 0.93 | HTR7 (0.37) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL8659391 | 0.91 | HTR7 (0.39) | HTR7CHRM2CHRM1KDM4EMEN1 | |
| SCHEMBL8655425 | 0.89 | HTR7 (0.38) | HTR7CHRM2CHRM1KDM4EALDH1A1 | |
| SCHEMBL8658396 | 0.89 | HTR7 (0.41) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL8658434 | 0.89 | HTR7 (0.32) | HTR7CHRM2CHRM1 | |
| SCHEMBL8659153 | 0.88 | HTR7 (0.37) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL8656805 | 0.86 | HTR7 (0.38) | HTR7CHRM2CHRM1KDM4EALDH1A1 | |
| SCHEMBL8659398 | 0.86 | HTR7 (0.37) | HTR7CHRM2CHRM1KDM4EHSD17B10 | |
| SCHEMBL8655755 | 0.85 | HTR7 (0.41) | HTR7CHRM2CHRM1GRIN2BGRIN1 | |
| SCHEMBL8661783 | 0.85 | GLA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |