Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659308 | 0.93 | SIGMAR1 (0.35) | SIGMAR1HTR7ALDH1A1TSHRTP53 | |
| SCHEMBL8655425 | 0.91 | HTR7 (0.38) | SIGMAR1HTR7ALDH1A1KDM4ETSHR | |
| SCHEMBL8659398 | 0.90 | HTR7 (0.37) | HTR7KDM4ETSHRCYP1A2CYP2D6 | |
| SCHEMBL8658143 | 0.89 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8659391 | 0.89 | HTR7 (0.39) | SIGMAR1HTR7ALDH1A1KDM4ETSHR | |
| SCHEMBL8658006 | 0.89 | HTR7 (0.39) | SIGMAR1HTR7 | |
| SCHEMBL8659538 | 0.86 | HTR7 (0.36) | SIGMAR1HTR7ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8654695 | 0.85 | HRH3 (0.32) | SIGMAR1ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL7307085 | 0.85 | SIGMAR1 (0.38) | SIGMAR1HTR7ALDH1A1TSHRTP53 | |
| SCHEMBL8655407 | 0.84 | HTR7 (0.40) | HTR7ALDH1A1KDM4EKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |