Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657864 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TSHRFAAHHTR7 | |
| SCHEMBL8657712 | 0.93 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HTR7HTR1A | |
| SCHEMBL8661291 | 0.92 | KMT2A (0.45) | SMN1; SMN2ALDH1A1TSHRFAAHKMT2A | |
| SCHEMBL8656276 | 0.90 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TSHRFAAHKMT2A | |
| SCHEMBL8655178 | 0.90 | ACHE (0.45) | FAAH | |
| SCHEMBL8654558 | 0.90 | CACNA1G (0.43) | SMN1; SMN2ALDH1A1KMT2AHTR7HTR1A | |
| SCHEMBL8654748 | 0.88 | ACHE (0.46) | FAAH | |
| SCHEMBL8657977 | 0.88 | ACHE (0.44) | FAAH | |
| SCHEMBL8657670 | 0.86 | KMT2A (0.44) | ALDH1A1TSHRKMT2AHTR7HTR1A | |
| SCHEMBL8654661 | 0.86 | CACNA1G (0.43) | SMN1; SMN2ALDH1A1KMT2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |