Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655680 | 0.85 | MAOB (0.47) | MAOBPDGFRBDYRK1ASYKTAAR1 | |
| SCHEMBL10886759 | 0.84 | PDGFRB (0.46) | MAOBHRH2HRH3PDGFRBNPC1 | |
| SCHEMBL8655655 | 0.83 | SLC7A5 (0.39) | NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL4861236 | 0.82 | LOXL2 (0.42) | PDGFRBMAPTMAPK1 | |
| SCHEMBL8091110 | 0.81 | MAOB (0.38) | MAOBHRH2HRH3PDGFRBSYK | |
| SCHEMBL8656924 | 0.81 | MPO (0.41) | MAOBHRH2HRH3RAB9AALDH1A1 | |
| SCHEMBL5674038 | 0.81 | MAOA (0.43) | HRH2HRH3SMN1; SMN2TAAR1TLR8 | |
| SCHEMBL5673490 | 0.80 | HRH1 (0.46) | HRH2HRH3 | |
| SCHEMBL1927324 | 0.80 | MAOA (0.42) | HRH2HRH3MAPTTAAR1TLR8 | |
| SCHEMBL11048397 | 0.79 | PDGFRB (0.47) | PDGFRBNPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |