Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654623 | 0.78 | ESR1 (0.44) | ESR1ESR2CYP2D6SIGMAR1KCNH2 | |
| SCHEMBL8653155 | 0.78 | ESR1 (0.39) | ESR1ESR2CYP2D6 | |
| SCHEMBL8636932 | 0.71 | ESR1 (0.51) | ESR1ESR2KCNH2XDH | |
| SCHEMBL8637238 | 0.71 | XDH (0.49) | ESR1ESR2CYP2D6XDH | |
| SCHEMBL7647862 | 0.63 | ESR1 (0.61) | ESR1ESR2SIGMAR1HRH1 | |
| SCHEMBL8641220 | 0.61 | ESR1 (0.62) | ESR1ESR2CYP2D6SIGMAR1KCNH2 | |
| SCHEMBL9027633 | 0.59 | ESR1 (0.43) | ESR1ESR2SIGMAR1KCNH2HRH1 | |
| SCHEMBL8196023 | 0.58 | ESR1 (0.44) | ESR1ESR2CYP2D6SIGMAR1KCNH2 | |
| SCHEMBL8654530 | 0.58 | PTPN1 (0.37) | ESR1ESR2 | |
| SCHEMBL7367096 | 0.57 | HRH3 (0.72) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516257-B1 | Phenylbenzo[b]furans and -thiophenes, procedures for their preparation, and pharmaceutical compositions containing the same | SCHERING AG (DE) | 1998-08-05 | — | — | EP | claimed |