Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18537152 | 0.75 | NQO2 (0.46) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL14613213 | 0.71 | MPO (0.59) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL14447257 | 0.71 | MTNR1B (0.46) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL11809364 | 0.69 | METAP1 (0.46) | METAP1ACHEALDH1A1KDM4EDRD2 | |
| SCHEMBL9282321 | 0.69 | HTR6 (0.37) | CA1CA2 | |
| SCHEMBL8349133 | 0.68 | NQO2 (0.62) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL11769186 | 0.68 | NQO2 (0.59) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL11769868 | 0.68 | NQO2 (0.59) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL7034109 | 0.68 | DRD2 (0.41) | NQO2MTNR1AMTNR1BMETAP1ACHE | |
| SCHEMBL5981019 | 0.68 | MPO (0.48) | MTNR1BMETAP1ACHEMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843670-A1 | 1-[2-(2,3-DIHYDRO-1H-INDEN-1-YL)ETHYL]-4-(NAPHTHALEN-1-YL)PIPERAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006155-A1 | 1-[2-(2,3-DIHYDRO-1H-INDEN-1-YL)ETHYL]-4-(NAPHTHALEN-1-YL)PIPERAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-02-20 | — | — | WO | disclosed |
| EP-0668273-A1 | Derivatives of 1-2-(1H-inden-3-yl)ethyl-4-(naphtalen-1-yl)-piperazin, their preparation and their therapeutical use | SYNTHELABO (FR) | 1995-08-23 | — | — | EP | disclosed |