SCHEMBL8655922

SCHEMBL8655922

CSc1nc(C=O)[nH]c1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
NUDT1 P36639 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7032304 0.75
SCHEMBL5510095 0.71
SCHEMBL8654119 0.71 GAA (0.30) GAA
SCHEMBL15819878 0.67
SCHEMBL9377845 0.64 HTT (0.39) NUDT1MAPT
SCHEMBL8663152 0.63 HTT (0.32) GAA
SCHEMBL11077687 0.61 ALDH1A1 (0.34) GAAMAPT
SCHEMBL8663358 0.61 DAGLA (0.32)
SCHEMBL7253470 0.60 L3MBTL1 (0.39) GAAMAPT
SCHEMBL14306613 0.60 CHRNB2 (0.41) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811445-A ANGIOTENSIN II INHIBITORS ROUSSEL UCLAF (FR) 1998-09-22 US disclosed