Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474748 | 0.89 | NPSR1 (0.41) | ALDH1A1LMNACYP26A1TDP1CNR2 | |
| SCHEMBL8654208 | 0.87 | LMNA (0.37) | TP53ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL8654752 | 0.81 | ALDH1A1 (0.41) | TP53RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8651359 | 0.81 | CYP26A1 (0.39) | TP53RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8653680 | 0.79 | TAS1R3 (0.45) | TP53RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6481350 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNAGAAL3MBTL1 | |
| SCHEMBL6483622 | 0.79 | NPSR1 (0.41) | ALDH1A1LMNAL3MBTL1CNR2CNR1 | |
| SCHEMBL7961964 | 0.74 | GPR88 (0.46) | RAB9ALMNAGAAMMP9MEN1 | |
| SCHEMBL8654281 | 0.72 | LMNA (0.40) | TP53ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL7959929 | 0.72 | LPAR1 (0.43) | TP53RAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847211-A | Substituted 1H-3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| US-5622917-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |