Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYTH2 | Q99418 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KAT7 | O95251 | 1/20 | 0.39 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661919 | 0.91 | CYTH2 (0.46) | CYTH2FFAR4METAP2KAT6AMCL1 | |
| SCHEMBL8660309 | 0.90 | FFAR4 (0.45) | CYTH2FFAR4KAT6AKMT2AHSD17B2 | |
| SCHEMBL8659971 | 0.89 | ERAP1 (0.47) | CYTH2FFAR4KAT6AHSD17B2KIF11 | |
| SCHEMBL8659487 | 0.88 | FFAR4 (0.45) | CYTH2FFAR4METAP2KAT6AMCL1 | |
| SCHEMBL8663509 | 0.88 | FFAR4 (0.47) | CYTH2FFAR4KAT6AMEN1KMT2A | |
| SCHEMBL8657903 | 0.87 | PGAM1 (0.45) | FFAR4HSD17B2TSHR | |
| SCHEMBL8661525 | 0.87 | KIF11 (0.55) | CYTH2FFAR4KAT6AKIF11 | |
| SCHEMBL8656815 | 0.86 | CYTH2 (0.51) | CYTH2FFAR4METAP2KAT6AMCL1 | |
| SCHEMBL8661551 | 0.86 | FFAR4 (0.42) | CYTH2FFAR4KAT6AKMT2AHSD17B2 | |
| SCHEMBL8660556 | 0.85 | FFAR4 (0.45) | CYTH2FFAR4METAP2KAT6AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |