Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.45 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663509 | 0.92 | FFAR4 (0.47) | FFAR4CYTH2KAT6AKMT2AMEN1 | |
| SCHEMBL8660556 | 0.90 | FFAR4 (0.45) | FFAR4CYTH2METAP2KAT6AKMT2A | |
| SCHEMBL8660484 | 0.89 | FFAR4 (0.44) | FFAR4CYTH2KAT6AKMT2AMEN1 | |
| SCHEMBL8658203 | 0.88 | FFAR4 (0.43) | FFAR4CYTH2METAP2KAT6AKMT2A | |
| SCHEMBL8656202 | 0.88 | CYTH2 (0.46) | FFAR4CYTH2METAP2KAT6AKMT2A | |
| SCHEMBL8660309 | 0.88 | FFAR4 (0.45) | FFAR4CYTH2KAT6AKMT2AACLY | |
| SCHEMBL8656166 | 0.87 | GAA (0.44) | FFAR4CYTH2KAT6AKMT2AGAA | |
| SCHEMBL8659971 | 0.86 | ERAP1 (0.47) | FFAR4CYTH2KAT6AACLY | |
| SCHEMBL8661428 | 0.85 | CYTH2 (0.54) | FFAR4CYTH2METAP2KAT6AKMT2A | |
| SCHEMBL8661919 | 0.85 | CYTH2 (0.46) | FFAR4CYTH2METAP2KAT6AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |