Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 2/20 | 0.52 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 5/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659348 | 0.89 | MEN1 (0.47) | PNLIPGCGRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8663057 | 0.87 | LMNA (0.48) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL8658796 | 0.84 | PNLIP (0.62) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL10962432 | 0.83 | ESRRA (0.50) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL8659354 | 0.83 | LMNA (0.47) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL8659719 | 0.82 | PYGL (0.47) | PNLIPLMNANPSR1L3MBTL1NPC1 | |
| SCHEMBL11133448 | 0.82 | STK39 (0.55) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL8659680 | 0.81 | LMNA (0.46) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL10495970 | 0.81 | LMNA (0.46) | PNLIPGCGRLMNANPSR1L3MBTL1 | |
| SCHEMBL8658068 | 0.81 | LMNA (0.45) | PNLIPGCGRLMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |