Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720585 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL4337616 | 0.86 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5720589 | 0.84 | MMP9 (0.37) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5720606 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8656363 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL5720607 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL11577887 | 0.69 | MAPT (0.49) | ALDH1A1SMN1; SMN2CYP3A4CA2TSHR | |
| SCHEMBL5720659 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMAPK1MMP9 | |
| SCHEMBL13259608 | 0.67 | CYP3A4 (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL4579017 | 0.67 | KDM4E (0.43) | ALDH1A1KDM4ELMNAMAPK1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611696-B2 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS B.V. (NL) | 2009-11-03 | — | — | US | claimed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | claimed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | claimed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | claimed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | claimed |
| US-7611696-B2 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS B.V. (NL) | 2009-11-03 | — | — | US | disclosed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | disclosed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DHPS, DSG1, DHODH | ALDH1A1 154/4885KDM4E 1689/4885SMN1; SMN2 4037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.