Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643326 | 0.88 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL6742103 | 0.87 | TMPRSS4 (0.50) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| Gentisic Acid Ethanolamide SCHEMBL29379843 | 0.79 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| Gentisic Acid Ethanolamide SCHEMBL1179368 | 0.79 | NAAA (0.65) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL21884529 | 0.79 | CDK1 (0.49) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980647 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980687 | 0.76 | CDK1 (0.82) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980880 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL8980561 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL6617465 | 0.76 | NPC1 (0.52) | KDM4EALDH1A1MAPTTMPRSS4P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566018-B1 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO SPA (IT) | 1998-08-05 | — | — | EP | disclosed |
| US-5480882-A | Benzoxazinone and benzothiazinone derivatives having cardiovascular activity | ITALFARMACO S.P.A. (IT) | 1996-01-02 | — | — | US | disclosed |
| EP-0566018-A2 | Benzoxazinone and benzothiazinone derivatives endowed with cardiovascular activity | ITALFARMACO S.p.A. (IT) | 1993-10-20 | — | — | EP | disclosed |