Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949941 | 0.84 | EPHX2 (0.45) | L3MBTL1ALDH1A1GLAHPGDSLC18A3 | |
| SCHEMBL7209767 | 0.83 | EPHX2 (0.47) | L3MBTL1ALDH1A1GLAHPGDLMNA | |
| SCHEMBL7368098 | 0.80 | LMNA (0.49) | L3MBTL1ALDH1A1GLAHPGDLMNA | |
| SCHEMBL8657131 | 0.79 | GBA1 (0.50) | GBA1SLC6A2SLC6A4HRH1L3MBTL1 | |
| SCHEMBL1477277 | 0.76 | GBA1 (0.50) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL9310454 | 0.75 | GBA1 (0.49) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| SCHEMBL8326384 | 0.72 | GBA1 (0.42) | GBA1SLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL9385814 | 0.71 | GBA1 (0.45) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| SCHEMBL20677801 | 0.71 | GBA1 (0.45) | GBA1HRH1L3MBTL1ALDH1A1GLA | |
| Piperazine SCHEMBL4405486 | 0.70 | CES2 (0.47) | L3MBTL1ALDH1A1GLAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | claimed |