Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657131 | 0.87 | GBA1 (0.50) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL7368098 | 0.77 | LMNA (0.49) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL12950567 | 0.74 | L3MBTL1 (0.47) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL1155730 | 0.74 | FAAH (0.55) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL8669232 | 0.72 | AKR1B1 (0.46) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL11127228 | 0.72 | POLB (0.51) | ALDH1A1EPHX2 | |
| SCHEMBL6949941 | 0.72 | EPHX2 (0.45) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL7209767 | 0.71 | EPHX2 (0.47) | LMNAL3MBTL1ALDH1A1GLAHPGD | |
| SCHEMBL9537261 | 0.71 | CYP19A1 (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL66721 | 0.71 | CES1 (0.55) | L3MBTL1ALDH1A1CES2CES1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |