Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL741638 | 0.76 | KMT2A (0.47) | KMT2AL3MBTL1KLK7KLK5FKBP1A | |
| SCHEMBL30440711 | 0.76 | KMT2A (0.51) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL4033681 | 0.72 | CPB1 (0.54) | KMT2AL3MBTL1PDE4BCTSLSYK | |
| SCHEMBL12873055 | 0.71 | KMT2A (0.47) | KMT2AL3MBTL1KLK7KLK5PDE4B | |
| SCHEMBL27978282 | 0.71 | FKBP1A (0.52) | KMT2AL3MBTL1FKBP1APDE4BCTSL | |
| SCHEMBL12667212 | 0.70 | KMT2A (0.63) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL1864036 | 0.70 | KMT2A (0.63) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL2670623 | 0.70 | KMT2A (0.63) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL6370475 | 0.70 | KMT2A (0.63) | KMT2AL3MBTL1CTSLSYKALDH1A1 | |
| SCHEMBL16523966 | 0.70 | KMT2A (0.63) | KMT2AL3MBTL1CTSLSYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871608-A1 | NOVEL MONOFUNCTIONALISED EDTA, DTPA AND TTHA DERIVATIVES AND THEIR USE IN MEDICAL DIAGNOSIS AND THERAPY | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025305-A1 | NOVEL MONOFUNCTIONALISED EDTA, DTPA AND TTHA DERIVATIVES AND THEIR USE IN MEDICAL DIAGNOSIS AND THERAPY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-07-17 | — | — | WO | disclosed |