Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657241 | 1.00 | ALOX15 (0.48) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9842483 | 1.00 | ALOX15 (0.48) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11146185 | 0.83 | ALDH1A1 (0.50) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14536877 | 0.83 | ALOX15 (0.60) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9572187 | 0.83 | ALDH1A1 (0.50) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9572183 | 0.83 | ALDH1A1 (0.50) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9720615 | 0.83 | LMNA (0.38) | ALOX15ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9720620 | 0.83 | LMNA (0.38) | ALOX15ALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9073790 | 0.82 | ALOX15 (0.48) | ALOX15ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9073787 | 0.82 | ALOX15 (0.48) | ALOX15ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461401-A1 | Process for the preparation of dialkyl, pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate | AMERICAN CYANAMID COMPANY (US) | 1991-12-18 | — | — | EP | claimed |
| US-5840904-A | Fluoro-pyridine-2,3-dicarboxylic anhydrides which are intermediates for herbicidal pyridine-2,3-dicarboximides | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| US-5679622-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5101067-A | Chemical intermediates for pyridinedicarboxylic acid esters, herbicides | WACKER-CHEMIE GMBH (DE) | 1992-03-31 | — | — | US | disclosed |
| EP-0461401-A1 | Process for the preparation of dialkyl, pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate | AMERICAN CYANAMID COMPANY (US) | 1991-12-18 | — | — | EP | disclosed |
| US-5008392-A | Reacting 2,3-dihalomaleic acid esters with ammonia or salts, reacting product with alpha, B-unsaturated aldehydes or ketones | WACKER-CHEMIE GMBH (DE) | 1991-04-16 | — | — | US | disclosed |