Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720620 | 1.00 | LMNA (0.38) | LMNAHCAR2ALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL9720639 | 0.88 | ALDH1A1 (0.47) | LMNAHCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9720634 | 0.88 | ALDH1A1 (0.47) | LMNAHCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9720649 | 0.84 | HCAR2 (0.41) | LMNAHCAR2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9720644 | 0.84 | HCAR2 (0.41) | LMNAHCAR2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8657246 | 0.83 | ALOX15 (0.48) | LMNAALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8657241 | 0.83 | ALOX15 (0.48) | LMNAALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9842483 | 0.83 | ALOX15 (0.48) | LMNAALOX15ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28810132 | 0.80 | HCAR2 (0.39) | LMNAHCAR2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6361599 | 0.78 | LMNA (0.40) | LMNAHCAR2ALOX15ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5101067-A | Chemical intermediates for pyridinedicarboxylic acid esters, herbicides | WACKER-CHEMIE GMBH (DE) | 1992-03-31 | — | — | US | disclosed |
| US-5008392-A | Reacting 2,3-dihalomaleic acid esters with ammonia or salts, reacting product with alpha, B-unsaturated aldehydes or ketones | WACKER-CHEMIE GMBH (DE) | 1991-04-16 | — | — | US | disclosed |