Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661385 | 0.86 | EPHX1 (0.47) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL5998425 | 0.78 | ALPI (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL7346855 | 0.77 | EPHX1 (0.51) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL28120920 | 0.76 | MMP9 (0.51) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL2722699 | 0.70 | ELANE (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL1053745 | 0.70 | ELANE (0.53) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL6332337 | 0.70 | MMP2 (0.44) | CA1CA2SMN1; SMN2HDAC1ALDH1A1 | |
| SCHEMBL1122643 | 0.69 | KEAP1 (0.45) | EPHX1PKMCA1CA2SMN1; SMN2 | |
| SCHEMBL7351481 | 0.69 | ALPI (0.55) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL8658264 | 0.69 | CYP2C19 (0.42) | PKMCA1CA2SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |