Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661391 | 0.83 | ALDH1A1 (0.43) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL5900661 | 0.81 | FABP4 (0.44) | ALDH1A1 | |
| SCHEMBL5998430 | 0.78 | CYP2C19 (0.47) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL23174395 | 0.77 | CYP2C19 (0.46) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL8660531 | 0.73 | KEAP1 (0.39) | CYP2C19CA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL637029 | 0.70 | CYP2C19 (0.53) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL637452 | 0.70 | CYP2C19 (0.53) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL1231305 | 0.70 | CYP2C19 (0.53) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL1383474 | 0.69 | CYP2C19 (0.67) | CYP2C19GABBR2GABBR1ALDH1A1CYP1A2 | |
| SCHEMBL4401320 | 0.69 | CA1 (0.50) | CA1CA2ALDH1A1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |