Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656240 | 0.91 | PKM (0.35) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8658466 | 0.91 | CYP1A2 (0.38) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8655682 | 0.90 | S1PR1 (0.32) | RECQLSMN1; SMN2S1PR1 | |
| SCHEMBL8656871 | 0.88 | ITGB3 (0.32) | ALDH1A1GAAHTR7RECQLSMN1; SMN2 | |
| SCHEMBL8659077 | 0.88 | GAA (0.34) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8657864 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHTR7SMN1; SMN2 | |
| SCHEMBL8655443 | 0.85 | ITGB3 (0.32) | GAARECQLSMN1; SMN2 | |
| SCHEMBL8659427 | 0.84 | HTR7 (0.41) | HTR7 | |
| SCHEMBL8656723 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8658456 | 0.84 | GAA (0.34) | ALDH1A1KDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |